introduction to sickle cell anemia pdf

To ascertain the prevalence of and risk factors for obstructive sleep apnea syndrome (OSAS) in children with sickle cell anemia (SCA). 0000001947 00000 n What is a balanced diet? <> On May 16, 1972, the National Sickle Cell Anemia Control Act was signed into law. 0000006788 00000 n The defective gene is called hemoglobin S, which changes the shape of the red blood cells from circular to crescent- or sickle-shaped. H��W]o�F}ׯ��va�9�dP���"馎����-�%6�%��_�g��D��r#]��}�7��?�|�{��$��o���n�>s�h����fQ�)����n��j�MU[��ł����g��jf����|. 0000001925 00000 n %���� 0000050650 00000 n 0000004049 00000 n 0000002298 00000 n In this chapter we will discuss about red cell indices and also about classification of anemia. 0000007195 00000 n SCD results from any combination of the sickle cell gene with any other abnormal β-globin gene and there are many types of SCD. ���E�=�2�0d��8H�3q�10060����תz���a�U��Y����1�3��İ(T�ϰ���U�VF �;;d�3�2�3t1j1���,�L@��u̟��Lk�K��lG ���] endstream endobj 843 0 obj 483 endobj 822 0 obj << /Type /Page /Parent 817 0 R /Resources << /ColorSpace << /CS2 830 0 R /CS3 829 0 R >> /ExtGState << /GS2 840 0 R /GS3 841 0 R >> /Font << /TT4 827 0 R /TT5 823 0 R /TT6 824 0 R /TT7 833 0 R >> /ProcSet [ /PDF /Text ] >> /Contents 831 0 R /MediaBox [ 0 0 612 792 ] /CropBox [ 0 0 612 792 ] /Rotate 0 /StructParents 0 >> endobj 823 0 obj << /Type /Font /Subtype /TrueType /FirstChar 32 /LastChar 122 /Widths [ 278 0 0 0 0 0 0 0 333 333 0 0 278 333 278 0 556 556 556 0 556 556 0 556 556 0 333 0 0 0 0 0 0 722 722 722 722 667 611 778 0 278 0 0 611 833 722 778 667 778 722 667 611 722 0 944 0 667 0 0 0 0 0 0 0 556 611 556 611 556 333 611 611 278 0 556 278 889 611 611 611 0 389 556 333 611 556 778 0 556 500 ] /Encoding /WinAnsiEncoding /BaseFont /EMFPCA+Arial,Bold /FontDescriptor 825 0 R >> endobj 824 0 obj << /Type /Font /Subtype /TrueType /FirstChar 32 /LastChar 121 /Widths [ 278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 667 0 0 0 611 0 0 0 0 0 0 833 0 0 0 0 722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 556 0 500 556 556 0 556 0 222 0 0 222 0 556 556 0 0 333 500 0 0 0 0 0 500 ] /Encoding /WinAnsiEncoding /BaseFont /EMFPEK+Arial,Italic /FontDescriptor 828 0 R >> endobj 825 0 obj << /Type /FontDescriptor /Ascent 905 /CapHeight 718 /Descent -211 /Flags 32 /FontBBox [ -628 -376 2000 1010 ] /FontName /EMFPCA+Arial,Bold /ItalicAngle 0 /StemV 144 /FontFile2 835 0 R >> endobj 826 0 obj << /Type /FontDescriptor /Ascent 905 /CapHeight 718 /Descent -211 /Flags 32 /FontBBox [ -665 -325 2000 1006 ] /FontName /EMFPAA+Arial /ItalicAngle 0 /StemV 94 /FontFile2 836 0 R >> endobj 827 0 obj << /Type /Font /Subtype /TrueType /FirstChar 32 /LastChar 121 /Widths [ 278 0 0 0 0 0 0 0 0 0 0 0 278 0 278 0 556 0 556 0 0 556 0 556 0 0 278 0 0 0 0 0 0 667 667 0 0 0 0 0 0 278 0 0 0 0 0 0 667 0 722 667 611 722 0 0 0 0 0 0 0 0 0 0 0 556 556 500 556 556 278 556 556 222 0 500 222 833 556 556 556 0 333 500 278 556 500 722 0 500 ] /Encoding /WinAnsiEncoding /BaseFont /EMFPAA+Arial /FontDescriptor 826 0 R >> endobj 828 0 obj << /Type /FontDescriptor /Ascent 905 /CapHeight 0 /Descent -211 /Flags 96 /FontBBox [ -517 -325 1082 1025 ] /FontName /EMFPEK+Arial,Italic /ItalicAngle -15 /StemV 0 /FontFile2 839 0 R >> endobj 829 0 obj /DeviceGray endobj 830 0 obj [ /ICCBased 837 0 R ] endobj 831 0 obj << /Filter /FlateDecode /Length 832 0 R >> stream ��AJ�8�b��!�C��,U��V��G@yw��n�,[L���0��d�'�l6�N�2�|��U���;�?���yK�qi!��\�N|;�f�ҠI�d���1��b�[�Y��*c�VC�cBBQ&N�b� 0000003185 00000 n <> 15.1 INTRODUCTION Anemia is a state of decreased red cell mass of blood leading to decreased oxygen carrying capacity of body. 0000047972 00000 n Sickle Cell Anemia: A Parent’s Guide for the Infant and Young Child Important Facts about Sickle Cell Anemia (Hb SS) Sickle cell anemia is the most common serious genetic disease in Black Americans. Anemias are classified etiologically and morphologically. 819 0 obj << /Linearized 1 /O 822 /H [ 1341 606 ] /L 339253 /E 72919 /N 16 /T 322754 >> endobj xref 819 25 0000000016 00000 n crisis's associated with sickle cell anemia fo und that those patients receiving Hydrea ( a drug thought to increase levels of hemoglobin in RBC) had half as many painful bouts as those Sickle cell anemia is a genetic disorder which causes the expression of defective hemoglobin resulting irregularly shaped red blood cells, known as “sickle cells.” These sickle cells cause problems in the body, often blocking blood flow and causing painful attacks and sometimes stroke. 0000004336 00000 n 0000007417 00000 n (bq��� ��-�4� �G���4 ���1L� �3 &500)[ )�a L Infection is the leading cause of death in young children with sickle cell disease. stream trailer << /Size 844 /Info 813 0 R /Root 820 0 R /Prev 322743 /ID[] >> startxref 0 %%EOF 820 0 obj << /Type /Catalog /Pages 815 0 R /Metadata 814 0 R /OpenAction [ 822 0 R /XYZ null null null ] /PageMode /UseNone /PageLabels 812 0 R /StructTreeRoot 821 0 R /PieceInfo << /MarkedPDF << /LastModified (D:20060124123302)>> >> /LastModified (D:20060124123302) /MarkInfo << /Marked true /LetterspaceFlags 0 >> >> endobj 821 0 obj << /Type /StructTreeRoot /RoleMap 126 0 R /ClassMap 129 0 R /ParentTreeNextKey 17 /ParentTree 191 0 R /K [ 189 0 R 193 0 R ] >> endobj 842 0 obj << /S 436 /L 567 /C 583 /Filter /FlateDecode /Length 843 0 R >> stream

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